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Matcha intake enhances systemic oxidative stress resistance and activates detoxification pathways in Drosophila
1Department of Liberal Arts and Human Development, Kanagawa University of Human Services, 1-10-1, Heiseicho, Yokosuka-shi, Kanagawa, Japan.
Bioscience, Biotechnology, and Biochemistry
|October 9, 2025
Abstract:
Matcha, a Japanese powdered green tea, enhances Drosophila resistance to oxidative stress. Transcriptome analysis shows activation of detoxification and antioxidant pathways, likely driven by caffeine-catechin synergy. Unlike green tea catechins, matcha did not extend lifespan under high-protein diets, underscoring complex physiological effects and validating Drosophila as a nutrigenomic model.
