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Updated: Jan 6, 2026

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Cell-based Assay Protocol for the Prognostic Prediction of Idiopathic Scoliosis Using Cellular Dielectric Spectroscopy
Published on: October 16, 2013
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Comparison Between Magnetically Controlled Growing Rods and Spinal Growth Guidance Surgery for Idiopathic Early-Onset
Francisco Narro Garcia1, Jennifer Hurry2, Richard E McCarthy3
1Department of Orthopedic Surgery, Washington University in St. Louis, St. Louis, MO.
Spine
|October 9, 2025
Summary
Spinal Growth Guidance (SpGG) and Magnetically Controlled Growing Rods (MCGR) show similar outcomes for idiopathic early-onset scoliosis (i-EOS) using 3D-TSL. SpGG demonstrated superior coronal curve correction and kyphosis maintenance over two years.
Area of Science:
- Pediatric Orthopedics
- Spinal Deformity Correction
- Growth Preservation Techniques
Background:
- Spinal Growth Guidance (SpGG) and Magnetically Controlled Growing Rods (MCGR) are used to manage severe progressive spinal deformities in children while preserving growth.
- Previous studies comparing these techniques relied on 2D measurements, potentially underestimating growth differences due to 3D spinal deformities.
Purpose of the Study:
- To compare the outcomes of SpGG and MCGR in patients with idiopathic early-onset scoliosis (i-EOS) using Three-Dimensional True Spine Length (3D-TSL).
- To evaluate spinal growth and deformity correction in i-EOS patients treated with either SpGG or MCGR over a minimum of two years.
Main Methods:
- A retrospective cohort study analyzing data from a multi-center database of i-EOS patients.
- Inclusion criteria required a minimum 2-year follow-up with perioperative and 2-year postoperative measurements.
- Outcomes were assessed using Three-Dimensional True Spine Length (3D-TSL) and coronal curve correction.
Main Results:
- SpGG showed a greater percentage of coronal curve correction (46%) compared to MCGR (34%) at two years (P=0.03).
- SpGG maintained maximal measured kyphosis (MMK) better than MCGR, with SpGG showing an increase of +9° versus MCGR's -7° (P<0.001).
- Both techniques increased T1-S1 height; 3D-TSL growth was 16.8 mm/year for SpGG and 14.2 mm/year for MCGR, with no significant difference (P=0.2).
Conclusions:
- Both SpGG and MCGR provide comparable spinal growth as measured by 3D-TSL at two years postoperatively.
- SpGG demonstrated superior coronal plane deformity correction and better maintenance of thoracic kyphosis compared to MCGR.
- These findings suggest SpGG may offer advantages in deformity control while preserving spinal growth in i-EOS.

