Related Experiment Video
Updated: Jan 15, 2026

Developing a Salivary Antibody Multiplex Immunoassay to Measure Human Exposure to Environmental Pathogens
Published on: September 12, 2016
IDQuAD: Infectious disease question and answering dataset
Soonchan Kwon1, Sujeong Hur1, Beakcheol Jang1
1Graduate School of Information, Yonsei University, Seoul, South Korea.
None:
While large language models (LLMs) have made significant advances in various fields, The study of applying LLMs to infectious disease-specific tasks has lagged behind. This study addresses this gap by introducing the Infectious Disease Question and Answering Dataset (IDQuAD), which is a novel dataset designed to train and evaluate LLMs in infectious disease-related queries. IDQuAD is constructed using medical papers, patents, and news, and employs innovative methodologies such as generating answers before questions and using counterfactual thinking to enhance the quality of the Question Answering (QA) pairs. In the experimental phase, we fine-tuned the Mistral-7B model on the IDQuAD dataset to test the effectiveness of our proposed datasets on LLM performance in QA tasks related to infectious diseases. The fine-tuned Mistral-7B model demonstrated substantial performance improvements, with its EM score increasing from 28.49% to 65.47% in the one-shot setting. Additionally, we evaluated other LLMs across various setups. Among all models tested, our fine-tuned model achieved the highest performance across metrics and settings. In conclusion, this study introduces IDQuAD as a foundational dataset for infectious disease research, demonstrating the effectiveness of fine-tuning LLMs and paving the way for future advances in dataset development and LLM refinement for infectious disease tasks.
Related Concept Videos
Steps in Outbreak Investigation
Infection
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
Intracellular Movement of Viruses and Bacteria
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
Immunodeficiency Diseases
There are three main causes of immunodeficiency...
Principles of Disease Surveillance

