Related Experiment Video
Updated: Jan 15, 2026

Author Spotlight: Investigating Wound Healing in Mice Models of Oronasal Fistulas
Published on: September 8, 2023
Overview of Etiology and Management of Epistaxis: Through the Mnemonic EPISTAXIS
Sedat Özbay1, Nuray Bayar Muluk2, Tarik Yagci3
1Department of Emergency Medicine, Sivas Numune Hospital, Sivas, Türkiye.
Objectives:
This study investigated the rate of application of various treatment steps for epistaxis using the mnemonic EPISTAXIS.
Methods:
Two thousand three hundred patients with epistaxis (1284 males and 1016 females) meeting the inclusion criteria from various centers in different regions of Turkey were enrolled in the study. All presented to the Emergency Department with epistaxis. Each patient was evaluated on the following items: cause of the epistaxis, accompanying diseases, and interventions performed (using the EPISTAXIS Mnemonic).
Results:
Idiopathic epistaxis was found in 80.0% of cases. Other causes included home accidents (7.7%), finger trauma (3.9%), rhinosinusitis (2.8%), and foreign bodies (2.4%). Hypertension was the most commonly detected accompanying condition (39.0%). Other diseases included diabetes mellitus (17.9%), blood disorders related to epistaxis (6.1%), and malignancy (5.9%). Intervention performed (EPISTAXIS Mnemonic) results were as follows:E xamination: Anterior epistaxis was detected at 95.0% and posterior epistaxis at 5.0%. P ressure (apply pressure over the nose with fingers) was applied in 48.3%. I rrigation (irrigate with warm water) was performed at 0.52%. S ilver nitrate: Cauterization was applied at a concentration of 22.86%. T ampons/nasal pack (anterior or posterior tampon) were applied at 73.86%. A frin: Vasoconstrictor spray (oxymetazoline spray) was applied to a tampon at 40.34%. T ransamine-tranexamic acid-applied on a tampon was performed at 17.0%. I nterventional radiology (embolization) was not performed (0.0%). S urgical consultation: ENT consultation was requested at 11.3%.
Conclusions:
For the treatment of epistaxis, the mnemonic EPISTAXIS (1) is suggested for a proper understanding and recall of appropriate treatment steps.
Related Concept Videos
Epistaxis
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Cardiopulmonary Resuscitation II: ACLS Airway Management
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Tonsillitis II: Management
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques
Asthma-IV: Nursing Management
First, in...

