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Quality of Life in Pediatric Hidradenitis Suppurativa: A Cross-Sectional Study

Charles B Lau1,2, Eric Xia1,2,3, Lisa Y Shen1,2

  • 1Department of Dermatology, Boston Medical Center, Boston, Massachusetts, USA.

Pediatric Dermatology
|October 9, 2025
PubMed

Insights

Pediatric Hidradenitis Suppurativa (HS) significantly impacts quality of life, even in early stages. Psychosocial screening is crucial for comprehensive care in children and adolescents with HS.

Area of Science:

  • Dermatology
  • Pediatrics
  • Psychology

Background:

  • Hidradenitis Suppurativa (HS) in pediatric populations is underrecognized and understudied.
  • The condition significantly affects psychosocial development during critical identity formation periods.

Purpose of the Study:

  • To assess the quality of life (QoL) burden in pediatric HS patients.
  • To evaluate the correlation between disease severity and QoL impairment.
  • To highlight the need for psychosocial support in pediatric HS.

Main Methods:

  • Cross-sectional survey of 18 pediatric HS patients.
  • Utilized Patient Health Questionnaire-2 (PHQ-2) for depression screening.
  • Employed Children's Dermatology Life Quality Index (CDLQI) and HiSQOL-Adolescent for QoL assessment.

Main Results:

  • QoL impairment generally correlated with HS disease severity.
  • Some patients with early-stage HS (Hurley Stage I) reported the highest QoL burden.
  • Early-stage HS patients screened positive for depression, indicating QoL is not solely tied to clinical severity.

Conclusions:

  • Clinical severity alone may not fully capture the lived experience of pediatric HS patients.
  • Psychosocial screening is essential for identifying and addressing the QoL burden.
  • Holistic care approaches are necessary for managing pediatric HS effectively.

Keywords:
CDLQIHiSQOL‐AdolescentHurley stagehidradenitis suppurativapediatric dermatologyquality of lifeunderserved populations

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