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Ten-Year Trends of Intravitreal Injection in South Korea Using the Health Insurance Review and Assessment Service
1Department of Ophthalmology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Korean Journal of Ophthalmology : KJO
|October 10, 2025
Summary
Intravitreal injections (IVI) in South Korea show a steady increase in patient numbers and procedures, particularly in primary care settings. This trend contributes to rising medical expenses, highlighting the need for resource allocation planning.
Area of Science:
- Ophthalmology
- Health Services Research
- Medical Economics
Background:
- Intravitreal injections (IVI) are a crucial treatment modality for various ocular conditions.
- Understanding the epidemiological trends and healthcare expenditure associated with IVI is essential for resource management.
Purpose of the Study:
- To analyze the annual trends of intravitreal injections (IVI) in South Korea from 2014 to 2023.
- To investigate patient demographics, healthcare facility utilization, and associated medical costs.
Main Methods:
- Retrospective analysis of data from the Health Insurance Review and Assessment Service (HIRA) Big Data Open Portal.
- Examination of IVI patient numbers and procedure counts, stratified by age group (excluding <40 years) and facility type.
- Analysis of healthcare expenditure trends related to IVI.
Main Results:
- A consistent rise in both the number of patients receiving IVI and the total number of injections administered, reaching 92,124 patients and 291,784 injections in 2023.
- Patients in their 70s represented the largest demographic for IVI recipients.
- Significant increase in IVI prevalence at primary healthcare facilities, rising from 20% in 2014 to 33% in 2023.
- Associated medical expenses showed a corresponding upward trend.
Conclusions:
- The utilization of intravitreal injections is increasing, with a notable shift towards primary healthcare settings.
- Rising medical expenses necessitate strategic planning for efficient healthcare resource allocation.
- This study provides critical data for future healthcare policy and resource management in ophthalmology.
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