THYROID NODULE FREQUENCY AND MALIGNANCY RISK ACCORDING TO ATA- 2015 AND ACR-TI-RADS CLASSIFICATION IN OBESE PATIENTS
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View abstract on PubMed
Summary
This summary is machine-generated.Obesity is linked to a higher prevalence of thyroid nodules. However, obesity does not increase the malignancy risk of these thyroid nodules, according to established ultrasonographic classification systems.
Area Of Science
- Endocrinology
- Radiology
- Oncology
Background
- Obesity is a growing global health concern.
- Thyroid nodules are common, and their evaluation relies on imaging and risk stratification.
- Understanding the relationship between obesity and thyroid nodule characteristics is crucial for clinical management.
Purpose Of The Study
- To compare thyroid nodule ultrasound findings, frequency, and malignancy risk between obese and non-obese individuals.
- To evaluate the utility of the American Thyroid Association (ATA) and American College of Radiology Thyroid Imaging Reporting and Data System (ACR-TIRADS) in assessing nodules in these groups.
Main Methods
- A comparative study included 111 obese subjects and 111 age- and sex-matched non-obese controls.
- Thyroid nodule malignancy risk was assessed using ATA and ACR-TIRADS classification systems.
- Fine needle aspiration biopsy (FNAB) and cytopathological evaluation (Bethesda system) were performed on suspicious nodules.
Main Results
- No significant differences were observed in age, sex, TSH levels, or thyroid volumes between the groups.
- Thyroid nodules were detected in 32.4% of obese subjects versus 19.8% of controls (p=0.046).
- The malignancy risk of thyroid nodules did not differ between obese and non-obese subjects based on ultrasonographic classifications.
Conclusions
- Obese individuals exhibit a higher frequency of thyroid nodules compared to non-obese individuals.
- Ultrasonographic classification systems (ATA and ACR-TIRADS) indicate no increased malignancy risk for thyroid nodules in obese patients.
- Further research may explore the underlying mechanisms linking obesity to increased nodule prevalence without altering malignancy potential.
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