A Case of Fatal Phlegmasia Cerulea Dolens: Challenges in Its Management

Alex S Nguyen1, Peter W Deucher2, Jamie Hill2

  • 1Pathology, William Carey University College of Osteopathic Medicine, Hattiesburg, USA.

Cureus
|October 10, 2025
PubMed

Insights

Phlegmasia cerulea dolens (PCD) is a rare, severe condition involving extensive deep vein thrombosis and compartment syndrome. Early recognition and improved management strategies are crucial for better patient outcomes.

Area of Science:

  • Vascular Surgery
  • Emergency Medicine
  • Critical Care Medicine

Background:

  • Phlegmasia cerulea dolens (PCD) is a rare but severe condition characterized by massive deep vein thrombosis (DVT) leading to lower extremity compartment syndrome.
  • PCD presents significant challenges due to high mortality and morbidity rates and a lack of established treatment protocols.

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