Mobile ECMO for inter-hospital transport of pediatric patients: experience from 22 cases

Yufan Yang1,2, Xiangni Wang1,3, Xiulan Lu1,2

  • 1Department of Intensive Care Unit, The School of Pediatrics, Hengyang Medical School, University of South China (Hunan Children's Hospital), Changsha, Hunan, China.

Frontiers in Pediatrics
|October 10, 2025
PubMed

Insights

Mobile extracorporeal membrane oxygenation (ECMO) transport is safe and effective for critically ill children. This study highlights successful inter-hospital transports, with most patients recovering and being discharged, demonstrating improved patient outcomes.

Area of Science:

  • Pediatric critical care medicine
  • Cardiopulmonary support technologies
  • Inter-hospital patient transfer protocols

Background:

  • Critically ill pediatric patients often require extracorporeal membrane oxygenation (ECMO) for life support.
  • Inter-hospital transport of these vulnerable patients presents unique logistical and clinical challenges.
  • Establishing safe and effective mobile ECMO transport is crucial for timely access to specialized care.

Purpose of the Study:

  • To summarize the management experience of inter-hospital transport for critically ill children on ECMO.
  • To provide evidence supporting the use of mobile ECMO for pediatric inter-hospital transport.
  • To identify key factors for successful mobile ECMO transport in critically ill children.

Main Methods:

  • Retrospective analysis of 22 critically ill pediatric patients transported via ambulance with ECMO support.
  • Evaluation of patient demographics, primary diagnoses, transport details, and clinical outcomes.
  • Review of management strategies including individual protection, transport procedures, equipment, teamwork, monitoring, and quality control.

Main Results:

  • 22 pediatric patients successfully underwent inter-hospital ECMO transport, with a median age of 76 months.
  • Primary diagnoses included ARDS, myocarditis, avian influenza, heart failure, and persistent pulmonary hypertension.
  • No transport complications were reported; 17 patients recovered and were discharged, while 5 developed multi-organ failure post-ECMO.
  • No infections occurred among transport staff.

Conclusions:

  • Mobile ECMO transport for critically ill children can be performed safely and effectively.
  • A well-equipped technical team and optimized procedures enhance the availability and safety of mobile ECMO.
  • This approach can save lives by enabling timely transfer of critically ill pediatric patients.
Abstract

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