Developing context-sensitive, comprehensive newborn care protocols: integrating technologies with clinical care

Grace Irimu1,2, Edith Gicheha3, Fareen Musa4

  • 1Department of Paediatrics and Child Health, University of Nairobi, Nairobi, Kenya.

Journal of Global Health
|October 10, 2025
PubMed

Insights

Preventable newborn deaths are reduced by evidence-based newborn care protocols and training in resource-constrained settings. This multidisciplinary approach standardizes care and improves collaboration in neonatal units.

Area of Science:

  • Global Health
  • Neonatal Medicine
  • Health Systems Strengthening

Background:

  • Millions of neonates die annually, primarily from preventable causes in resource-constrained settings (RCSs).
  • Sub-Saharan Africa faces the highest burden of neonatal mortality, with most deaths occurring in the first week of life.
  • The Newborn Essential Solutions and Technologies (NEST360) programme aims to reduce neonatal deaths through technology, training, and data in RCSs.

Purpose of the Study:

  • To document the development of evidence-based comprehensive newborn care protocols (NBU-Protocols) and a dissemination training program.
  • To inform scalable solutions for improving newborn care in resource-constrained settings.
  • To reduce preventable neonatal deaths through standardized care protocols.

Main Methods:

  • Developed NBU-Protocols through evidence review and iterative stakeholder feedback, including frontline health workers.
  • Piloted and revised protocols following a national stakeholder workshop.
  • Created a three-pronged dissemination training program (Newborn ETAT+) led by pediatricians, biomedical engineers, and nurses, incorporating interactive lectures, demonstrations, and hands-on practice.

Main Results:

  • NBU-Protocols include clinical care pathways, standard operating procedures for equipment, and procedural instructions for level 2 neonatal units (NBUs).
  • Protocols emphasize family-centered care and infection prevention, presented as user-friendly e-protocols.
  • The Newborn ETAT+ training program utilized a multidisciplinary approach with a significant focus on practical, hands-on learning.

Conclusions:

  • The NBU-Protocols and training model demonstrate the effectiveness of context-specific, multidisciplinary strategies.
  • These strategies can improve collaboration and standardize care in neonatal units within low- and middle-income countries (LMICs).
  • The approach offers a scalable solution for reducing neonatal mortality in resource-constrained settings.
Abstract

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