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[A study on the conversion between SMN1 and SMN2 genes]

Qiannan Guo1, Guiyu Lou, Li Wang

  • 1Department of Medical Genetic Center of Henan Provincial People's Hospital (People's Hospital of Zhengzhou University), Zhengzhou, Henan 450003, China. guoqn1984@aliyun.com; ychslshx_hn@aliyun.com.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi = Zhonghua Yixue Yichuanxue Zazhi = Chinese Journal of Medical Genetics
|October 10, 2025
PubMed
Summary

Gene conversion between SMN1 and SMN2 genes in healthy individuals aims to normalize copy numbers towards two. This process favors SMN1, influencing gene copy number regulation in the population.

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