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Updated: Jan 15, 2026

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An In Vitro Single-Molecule Imaging Assay for the Analysis of Cap-Dependent Translation Kinetics
Published on: September 15, 2020
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A data-driven fluorescent platform for monitoring amine dynamics in reactions
Zhen Liu1,2, Mingjun Wang1, Shayu Li1
1College of Chemistry and Chemical Engineering, Chongqing University, Chongqing, P. R. China. shayuli@cqu.edu.cn.
Abstract:
A novel luminophore DBPO enables real-time ratiometric tracking of amine dynamics through reversible deprotonation. Integrated with a QSPR model for aliphatic amines it reveals speciation effects in nucleophilic substitution kinetics and facilitates visual detection of seafood spoilage. This approach unites optical sensing with predictive modeling to decode reactive amine behavior.

