Clinical experience depicting wound regression trends with carePATCH: a case series

Area of Science:

• Regenerative Medicine
• Wound Healing Biology
• Clinical Dermatology

Background:

• Chronic wounds pose a significant clinical challenge, often failing to respond to standard treatments.
• Standard of Care (SoC) protocols may require adjunctive therapies for optimal outcomes in complex wound cases.

Purpose of the Study:

• To evaluate the clinical efficacy of carePATCH, a dehydrated amniotic membrane allograft, as an adjunct to SoC for hard-to-heal wounds.
• To assess wound surface area reduction and clinical parameters in patients receiving carePATCH alongside SoC.

Main Methods:

• A case series involving 13 patients (mean age 75.1 years) with hard-to-heal wounds unresponsive to SoC.
• carePATCH was applied as an adjunct to SoC post-debridement.
• Wound surface area and percentage area reduction (PAR) were measured at baseline, final application, and one week post-final application.

Main Results:

• Median PAR reached 77.4% at final application, increasing to 100% one week later.
• Statistically significant improvements in PAR were observed (p=0.017 at final application, p=0.003 at one week post-final application).
• Consistent wound surface area reduction was noted across various wound types, including venous leg ulcers and pressure ulcers.

Conclusions:

• carePATCH demonstrates encouraging results as an adjunct therapy for chronic wound management.
• The study supports positive clinical experiences and wound regression with carePATCH use.
• This amniotic membrane allograft shows promise in enhancing outcomes for non-healing wounds.