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Related Concept Videos

Esophageal Perforation-I: Introduction01:22

Esophageal Perforation-I: Introduction

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Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
844

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Methylene Blue vs Oral Water-soluble Contrast in Detecting Cervical Anastomotic Leak after Esophagectomy for Cancer Esophagus: A Comparative Study.

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Pacemaker lead perforations: a five-year study from a high-volume center in India.

Mohd Iqbal Dar1, Imran Hafeez2, Sheikh Mohamad Tahir2

  • 1Sher-i-Kashmir Institute of Medical Sciences, Srinagar, India. darmohdiqbal@yahoo.in.

The Egyptian Heart Journal : (EHJ) : Official Bulletin of the Egyptian Society of Cardiology
|October 10, 2025
PubMed
Summary
This summary is machine-generated.

Pacemaker lead perforation is a rare but serious complication of cardiac device implantation. Careful monitoring and nonsurgical management lead to favorable outcomes in most cases, with low mortality.

Keywords:
CIED lead perforationPacemaker lead perforationPericardial effusionPericardial tamponadeRV perforation

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Area of Science:

  • Cardiology
  • Medical Devices
  • Cardiac Electrophysiology

Background:

  • Device therapy for cardiac rhythm disturbances is increasing, along with associated complications.
  • Pacemaker lead perforation is a significant feared complication of cardiac device implantation.
  • This study evaluated clinical features, diagnosis, and outcomes of pacemaker lead perforation.

Purpose of the Study:

  • To assess the clinical presentation and outcomes of pacemaker lead perforation.
  • To determine the incidence and risk factors associated with lead perforation.
  • To evaluate the effectiveness of current management strategies.

Main Methods:

  • Prospective observational study.
  • Inclusion of 5493 patients undergoing temporary pacemaker (TPM) lead placement or CIED implantation.
  • Analysis of clinical features, diagnostic findings, and patient outcomes.

Main Results:

  • 23 lead-induced RV perforations occurred (0.42% incidence), mostly from TPM leads (78.2%).
  • Common complications included bradycardia (78.3%), capture loss (60.87%), and pericardial effusion (82.6%), with 8 cases requiring pericardiocentesis.
  • Mortality was 4.34%, with one death reported.

Conclusions:

  • Pacemaker lead perforation, though infrequent, presents with significant complications.
  • Careful monitoring and nonsurgical management strategies yield favorable outcomes.
  • The study highlights the importance of vigilant surveillance post-implantation.