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A double-edged sword of neo-substrate degradation in PROTACs

Zihan Song1, Chengze Duan1, Mingfei Wu1

  • 1School of Pharmaceutical Sciences, Hangzhou Medical College, Hangzhou, Zhejiang, China.

European Journal of Medicinal Chemistry
|October 10, 2025
PubMed
Abstract

Keywords:
CRBNDegradationIMiDsNeo-substratePROTACsSynergistic effect

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