ENDOSCOPIC INJECTION HEMOSTASIS AND LOCAL TREATMENT OF GASTRODUODENAL BLEEDING. LITERATURE REVIEW AND OWN...

Area of Science:

• Gastroenterology
• Endoscopic Surgery
• Pharmacology

Background:

• Gastric and duodenal ulcers are common, dangerous conditions often causing significant gastrointestinal bleeding.
• Current endoscopic hemostasis methods, while foundational, face challenges with high relapse rates and variable effectiveness.
• Effective management of gastroduodenal bleeding is crucial to prevent severe complications.

Purpose of the Study:

• To review modern endoscopic hemostasis approaches for ulcer bleeding.
• To highlight innovative local treatment methods and drug delivery systems.
• To assess strategies for improving treatment efficacy and reducing relapse.

Main Methods:

• Review of current literature on endoscopic hemostasis for gastroduodenal ulcers.
• Discussion of injection therapies, vasoconstrictors, and combined endoscopic techniques.
• Exploration of novel therapeutic delivery systems, including natural preparations like egg oil and Kalanchoe juice.
• Consideration of equipment protection during endoscopic procedures.

Main Results:

• Improved endoscopic hemostasis techniques enhance treatment outcomes for gastroduodenal ulcer bleeding.
• Novel drug delivery methods, such as egg oil and Kalanchoe juice, show promise for localized ulcer treatment.
• Utilizing additional manipulation channels can prevent endoscopic equipment damage.
• Advancements in hemostasis and local treatment reduce the risk of post-procedure bleeding recurrence.

Conclusions:

• Optimizing existing endoscopic hemostasis and local treatment methods is vital.
• Integrating innovative therapeutic strategies significantly increases the effectiveness of treating gastroduodenal ulcer bleeding.
• These advancements are critical for reducing relapse rates and improving patient outcomes in clinical practice.