Related Experiment Video
Updated: May 2, 2026
Predictive Measurement for Windlass Change in Length and Selected Treatment Outcomes in Chronic Plantar Fasciitis
Published on: March 1, 2024
Saturated saline immersion for the treatment of refractory plantar warts: An open-label, one-arm, single-center trial
Yinglin Xu1, Tingting Li1, Xinzheng Liang2
1Department of Dermatology, Zhujiang Hospital of Southern Medical University, Guangzhou, China.
Background:
Treating plantar warts (PWs) presents a significant challenge due to frequent treatment failures and recurrences. Current therapeutic approaches, such as salicylic acid, cryotherapy, and laser treatment, are destructive. There is a lack of painless and noninvasive treatment options for PWs.
Objective:
To evaluate the efficacy and safety of daily saturated saline immersion PWs over 6 months.
Methods:
This single-arm clinical trial enrolled 17 participants with PWs and failed standard treatments, who underwent daily 30-minute saturated saline immersion for 8 weeks. Effectiveness and safety were assessed.
Results:
After saturated saline immersion treatment, 98.3% of lesions (232/236) cleared, and 88.2% of participants (15/17) achieved complete remission (95% CI 63.3% to 97.4%) at week 8 compared to baseline. No recurrences occurred during the 6-month follow-up.
Limitations:
Single-arm design lacking active comparators, limited long-term follow-up for durability assessment.
Conclusion:
Daily saturated-salt-water immersion achieved high lesion- and patient-level clearance rates with painless and no short-term recurrence. Randomized controlled trials are warranted to confirm these findings.
