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Updated: Jan 15, 2026

Author Spotlight: Utilizing Venoplasty Balloon Model in Rodents to Simulate Surgical Interventions for Deep Veins
Published on: May 24, 2024
Technology, pharmacology, and clinical outcomes of sirolimus coated balloons for peripheral arterial interventions
Ruttiros Khonkarn1,2, Pranvera Ramadani3, Sheng Qi4
1Department of Pharmaceutical Science, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, Thailand.
Introduction:
Peripheral arterial intervention is a rapidly evolving field with a significant impact on an aging population.
Areas Covered:
Treatment concepts evolve rapidly, with new therapies providing sustainable and cost-effective solutions for complex patients.
Expert Opinion:
Metal stenting has been replaced by the 'leave-nothing-behind' approach, and plain balloon angioplasty devices have been replaced by drug-coated balloons (DCBs). While paclitaxel was initially used, sirolimus has more recently shown promising outcomes. This review article provides an overview of the technology and pharmacology behind sirolimus-coated balloons (SRL-DCB) and presents existing clinical evidence of their use.
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