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Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking
Published on: February 12, 2011
Reference Ranges for Cardiac Magnetic Resonance-Derived Atrioventricular Plane Displacement in Healthy Han Chinese
Bin Zhang1,2, Fenghai Liu3, Guoce Li3
1Graduate School, Tianjin Medical University, Tianjin, China.
Insights
This study establishes reference ranges for atrioventricular plane displacement (AVPD) in healthy Han Chinese adults using cardiac MRI. Age significantly influences AVPD, highlighting its importance in assessing myocardial function.
Area of Science:
- Cardiovascular imaging
- Cardiac mechanics
- Ventricular function assessment
Background:
- Atrioventricular plane displacement (AVPD) and cardiac valve plane displacement (CVPD) are key to longitudinal ventricular function.
- These parameters vary with age, but reference values for Han Chinese adults are lacking.
Purpose of the Study:
- To establish reference ranges for AVPD in healthy Han Chinese adults.
- Utilize cardiac magnetic resonance (MR) imaging for precise measurements.
Main Methods:
- Prospective, single-center study involving 200 healthy Han Chinese adults.
- 3.0 Tesla MR imaging with steady-state free precession (SSFP) sequence.
- Quantification of left ventricle (LVAVPD) and right ventricle (RVAVPD) using long-axis cine images.
Main Results:
- Mean LVAVPDavg was 14.0±1.5 mm and RVAVPDavg was 18.7±2.3 mm.
- No significant sex differences were found, but significant age-related variations were observed.
- Age, end-diastolic volume (EDV), and end-diastolic volume index (EDVi) were significant determinants of AVPD.
Conclusions:
- Presents normative LVAVPD and RVAVPD ranges for healthy Han Chinese adults.
- Demonstrates age-related changes and correlations with EDV, stroke volume (SV), and ejection fraction (EF).
- Supports the clinical utility of AVPD in myocardial function assessment.
Background:
Atrioventricular plane displacement (AVPD) and cardiac valve plane displacement (CVPD) are dominant contributors to the longitudinal component of ventricular pump function and vary with age; however, reference values are not available for Han Chinese adults.
Purpose:
To establish reference ranges for AVPD in healthy Han Chinese adult volunteers using cardiac magnetic resonance (MR).
Study Type:
Prospective, single-center study.
Population:
Two hundred healthy adult volunteers (45.0 ± 14.5 years; 49.5% male) were recruited between May and July 2024.
Field Strength/Sequence:
3.0 Tesla MR imaging; steady-state free precession (SSFP).
Assessment:
All participants underwent 3.0 Tesla cardiac MR during breath-holding at end-expiration. AVPD for the left ventricle (LVAVPD) and right ventricle (RVAVPD) was quantified using three long-axis cine images with manually inputted points. LVAVPD (average (avg), anterior (ant), inferior (inf), anterior-septal (ant-sep), inferior-lateral (inf-lat), inferior-septal (inf-sep), anterior-lateral (ant-lat)), as well as RVAVPD (average (avg), right ventricular outflow tract ( rvot ), and lateral (lat)), were recorded.
Statistical Tests:
Descriptive statistics; analysis of variance for age groups; multivariate linear regression; significance was set at p < 0.05.
Results:
Mean values were: LVAVPDavg, 14.0 ± 1.5 mm; LVAVPDant, 12.5 ± 1.7 mm; LVAVPDinf, 15.7 ± 2.1 mm; LVAVPDant-sep, 12.4 ± 2.0 mm; LVAVPDinf-lat, 15.6 ± 2.3 mm; LVAVPDinf-sep, 13.0 ± 1.9 mm; LVAVPDant-lat, 14.8 ± 2.0 mm; RVAVPDavg, 18.7 ± 2.3 mm; RVAVPDrvot, 20.7 ± 3.4 mm; RVAVPDlat, 22.6 ± 3.0 mm. No significant sex differences were observed; however, significant differences were noted across the age groups (G<45, G45-60, and G>60). Multivariate linear regression analysis identified age, end-diastolic volume (EDV), and end-diastolic volume index (EDVi) as significant independent determinants of AVPD.
Data Conclusion:
This study presents both LVAVPD and RVAVPD reference ranges in healthy Han Chinese adults and demonstrates age-related changes and correlations with EDV, stroke volume (SV), and ejection fraction (EF). These findings support the clinical utility of AVPD in myocardial function assessment.
Evidence Level:
N/A.
Technical Efficacy:
Stage 1.
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