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Updated: Jan 15, 2026

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Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
Published on: April 18, 2025
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Cranial reconstruction in the literature: A CiteSpace visualized bibliometric analysis
Jake Barsch1, Erion Sulaj2, John L Kilgallon2
1Department of Neurosurgery, Hackensack Meridian School of Medicine, 123 Metro Blvd, Nutley, NJ, 07110, USA. jake.barsch@hmhn.org.
Neurosurgical Review
|October 11, 2025
Summary
Cranioplasty research shows evolving trends in materials, with a rise in patient-specific implants for traumatic brain injury. The field is increasingly focused on surgical complications and clinical outcomes.
Area of Science:
- Neurosurgery and Biomedical Engineering
- Materials Science in Medical Devices
Background:
- Cranioplasty (CP) material selection lacks standardization, presenting diverse options for bone flap reconstruction.
- Understanding research evolution in CP materials is crucial for advancing reconstructive techniques.
Purpose of the Study:
- To conduct a bibliometric analysis of cranioplasty research from 2014-2024, focusing on material choice.
- To identify trends, key contributors, and knowledge structures in the cranioplasty material literature.
Main Methods:
- Bibliometric analysis of 933 publications from the Scopus database (2014-2024).
- Utilized R package 'bibliometrix' for data summarization and network visualization.
- Employed VOSviewer and CiteSpace for co-authorship, co-occurrence, and citation burst analyses.
Main Results:
- Significant increase in cranioplasty for traumatic brain injury (TBI) and use of patient-specific implants observed.
- Early research focused on material application; later trends emphasize surgical complications and clinical outcomes.
- The United States emerged as the leading contributor to cranioplasty material research.
Conclusions:
- Bibliometric analysis reveals a dynamic research landscape in cranioplasty materials.
- Keyword trends indicate a shift towards addressing practical challenges and patient outcomes.
- The study maps the foundational knowledge structure of cranioplasty material research over the last decade.
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