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Nutrition Effects on Brain Outcomes and Recovery in Stroke after Hospitalization (NOURISH): Randomized controlled
Laurel Cherian1, Puja Agarwal2, Klodian Dhana1
1Rush University Medical Center, Chicago, IL, USA.
Contemporary Clinical Trials
|October 11, 2025
Summary
The MIND diet may help prevent cognitive decline after stroke. This study investigated the MIND diet
Area of Science:
- Neurology
- Nutritional Science
- Public Health
Background:
- Stroke survivors have a doubled risk of dementia.
- Diet is a key modifiable factor for vascular health and cognitive function.
- Limited data exists on post-stroke cognitive decline prevention strategies.
Purpose of the Study:
- To evaluate the MIND diet's effect on cognitive changes in older adults post-acute ischemic stroke.
- To assess the MIND diet's efficacy in preventing cognitive impairment after stroke.
- To inform dietary guidelines for stroke patient care.
Main Methods:
- Phase III randomized controlled trial (NOURISH; NCT04337255).
- Participants (≥55 years) received MIND diet coaching or standard post-stroke care.
- Intervention lasted 24-36 months with cognitive, biomarker, and imaging assessments.
Main Results:
- N/A - Study ongoing, results pending.
- N/A - Study ongoing, results pending.
- N/A - Study ongoing, results pending.
Conclusions:
- The study will determine if the MIND diet can prevent cognitive impairment in stroke survivors.
- Findings will offer crucial insights for developing evidence-based dietary recommendations for post-stroke recovery and long-term brain health.
Keywords:
Acute ischemic stroke survivorsCognitive declineDiet interventionMIND dietary patternPhase 3 randomized clinical trialMore Related Videos
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