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Published on: April 28, 2015
Biosynthesis of Microbial Pigment-Mediated Nanoparticles and Its Biomedical Applications
Humma Niaz Malik1, Subhasree Ray1, Soumya Pandit1
1Department of Life Sciences, School of Bio-Sciences and Technology, Sharda University, Greater Noida, Uttar Pradesh, India.
Abstract:
Microbes are known to produce various bioactive compounds that find applications in the biomedical field. Out of many bioactive compounds, pigments synthesized from microbes have gained industrial attention. Pigments have been produced from various bacteria, fungi, and algae. Recently, microbial pigment-mediated nanoparticle (NP) synthesis is gaining importance due to its application in various fields. Various pigments such as melanin, phycocyanin, monascus, xanthomonadin, prodigiosin, carotenoid, flexirubin, canthaxanthin, and fucoxanthin have been utilized to generate different types of NPs with diverse shapes and sizes. Generally, silver and gold NPs have mostly been made using microbial pigments. The benefit of utilizing NPs produced through these pigments is that this method is eco-friendly and cost-effective. In addition to this, these NPs can be used in diverse biomedical sectors. These NPs act as anticancer, antibacterial, antifungal, and antioxidant agents. The present review sheds light on various microbial pigments that have been utilized for the synthesis of various NPs and their application in medicine and diagnostics and their future prospects.
Insights
Microbial pigments are eco-friendly sources for synthesizing nanoparticles (NPs). These biocompatible NPs show promise as anticancer, antibacterial, antifungal, and antioxidant agents for biomedical applications.
Area of Science:
- Biotechnology
- Nanotechnology
- Microbiology
Background:
- Microbes produce bioactive compounds with biomedical applications.
- Microbial pigments are gaining industrial and research attention.
- Microbial pigment-mediated nanoparticle (NP) synthesis is an emerging field.
Purpose of the Study:
- To review microbial pigments used for NP synthesis.
- To highlight the applications of these NPs in medicine and diagnostics.
- To discuss future prospects of microbial pigment-derived NPs.
Main Methods:
- Utilizing various microbial pigments (e.g., melanin, phycocyanin, carotenoids).
- Synthesizing different types of NPs (e.g., silver, gold) with diverse shapes and sizes.
- Investigating the biomedical applications of synthesized NPs.
Main Results:
- Diverse microbial pigments can mediate NP synthesis.
- Synthesized NPs exhibit anticancer, antibacterial, antifungal, and antioxidant properties.
- Microbial pigment-based NP synthesis is eco-friendly and cost-effective.
Conclusions:
- Microbial pigments offer a sustainable route for NP production.
- These NPs hold significant potential for medical and diagnostic applications.
- Further research can expand the utility of microbial pigment-derived NPs.
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