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Published on: November 19, 2012
Alcohol use disorder is associated with inpatient admission after mild traumatic brain injury
Vikas N Vattipally1, Patrick Kramer1, Kathleen R Ran1
1Department of Neurosurgery, Johns Hopkins University School of Medicine, United States.
Background:
Mild traumatic brain injury (mTBI) is commonly associated with alcohol use. We investigated how inpatient admission patterns after mTBI vary for patients with alcohol use disorder (AUD).
Methods:
This was a retrospective cohort study of patients with mTBI from the American College of Surgeons Trauma Quality Program dataset. Mixed regression models measured associations with inpatient admission, including among a subgroup of patients with AUD. Effect modification was tested for age, race, and acute intoxication.
Results:
78,937 patients with mTBI were included, and 7.0 % had AUD. AUD was associated with increased admission odds (OR, 1.83; 95 % CI, 1.67-2.01). Black patients and those presenting intoxicated had this effect reduced. Among a subgroup of patients with AUD, acute intoxication reduced admission odds (OR, 0.73; 95 % CI, 0.59-0.91).
Conclusions:
AUD increased inpatient admission odds after mTBI, while acute intoxication reduced these odds among patients with AUD. These findings help contextualize care for the common diagnostic constellation of mTBI and AUD.
Insights
Alcohol use disorder (AUD) increases hospital admission odds after mild traumatic brain injury (mTBI). However, acute intoxication decreased these odds in patients with AUD, impacting care for this common condition.
Area of Science:
- Trauma surgery
- Neuroscience
- Addiction medicine
Background:
- Mild traumatic brain injury (mTBI) frequently co-occurs with alcohol use.
- Understanding inpatient admission patterns for mTBI patients with alcohol use disorder (AUD) is crucial for effective care.
Purpose of the Study:
- To investigate how inpatient admission patterns differ for patients with mTBI who also have AUD.
- To analyze the impact of acute intoxication on admission rates within this patient group.
Main Methods:
- Retrospective cohort study utilizing the American College of Surgeons Trauma Quality Program dataset.
- Mixed regression models were employed to assess associations with inpatient admission.
- Effect modification by age, race, and acute intoxication was examined.
Main Results:
- The study included 78,937 mTBI patients, with 7.0% having AUD.
- AUD was significantly associated with increased odds of inpatient admission (OR, 1.83).
- Acute intoxication reduced admission odds among patients with AUD (OR, 0.73).
Conclusions:
- Alcohol use disorder elevates the likelihood of inpatient admission following mTBI.
- Acute intoxication appears to decrease admission odds for mTBI patients with AUD.
- Findings aid in managing the complex care needs of patients with co-occurring mTBI and AUD.
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