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Related Concept Videos

The Thyroid Gland01:23

The Thyroid Gland

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The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
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Related Experiment Video

Updated: Jan 15, 2026

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
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Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

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Primary squamous thyroid cancer: A case report.

Shuchang Dong1, Xuewen Wang2, Ziwen Zhou1

  • 1School of Clinical Medicine, Shandong Second Medical University, Weifang, Shandong 261000, P.R. China.

Oncology Letters
|October 13, 2025
PubMed
Summary
This summary is machine-generated.

Primary squamous cell carcinoma of the thyroid (PSCCT) is rare and aggressive. This case study shows a complete response using surgery, chemotherapy, and immunotherapy in a PD-L1 high expressor, suggesting optimized treatment strategies.

Area of Science:

  • Oncology
  • Thyroid Cancer Research
  • Immunotherapy

Background:

  • Primary squamous cell carcinoma of the thyroid (PSCCT) is a rare, aggressive malignancy with poor prognosis.
Keywords:
chemotherapyprimaryradiation oncologysquamous thyroid cancersurgery

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  • Standardized treatment guidelines for PSCCT are lacking, necessitating further research into effective therapeutic strategies.