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Mixed-Type Carotid Sinus Syndrome in a Patient With Advanced Laryngeal Cancer: A Case Report
Montaser Elkholy1, Naisargee Solanki1, Mohamed Abdelazeem2
1Department of Medicine, Detroit Medical Center, Wayne State University, Detroit, Michigan, USA.
Case Reports in Medicine
|October 13, 2025
Summary
Head and neck tumors can rarely cause carotid sinus syndrome (CSS), leading to syncope. This case highlights CSS in laryngeal cancer, emphasizing tumor compression as a cause and the need for multidisciplinary care.
Area of Science:
- Oncology
- Cardiology
- Neurology
Background:
- Head and neck tumors can rarely present with Carotid Sinus Syndrome (CSS).
- CSS is characterized by bradycardia, hypotension, and syncope.
- Advanced laryngeal cancer can potentially compress vital structures.

