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Updated: Aug 11, 2026

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
Published on: June 7, 2015
Development and characterization of composite hydrogels loaded with hawthorn flavonoid microcapsules: Application in
Shihao Lou1, Xiaojing Sun1, Ruobing Hao1
1College of Food and Biology, Hebei University of Science and Technology, Shijiazhuang 050000, China.
Abstract:
In this research, gelatin (GA) and k-carrageenan (CG) were employed as hydrogel matrix, and casein-hawthorn flavonoid microcapsules (CHM) were added as cross-linking agents and antioxidants to fabricate multifunctional composite hydrogels (GCH). Through the evaluation of physicochemical properties and mechanical strength, it was ascertained that GCH-25, prepared with a GA concentration of 25%, exhibited excellent water vapor permeability (WVP) and oxygen permeability (OP) properties, along with remarkable tensile strength and elongation at break. The cross-linking properties among GA, CG and CHM were also manifested reflected in the FTIR and XRD results. Meanwhile, the composite hydrogel with added CHM demonstrated good antioxidant and antibacterial activities. Cold pork preservation tests verified that GCH could inhibit the growth and reproduction of Pseudomonas aeruginosa, enabling cold pork to maintain a good appearance and morphology and extending its shelf life to 12 days. The results indicated that GCH was effective in inhibiting the growth and reproduction of Pseudomonas aeruginosa, representing an effective method for cold pork preservation. These findings highlight the potential of GCH-25 as a prospective antimicrobial packaging material for extending storage time.
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