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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
From Rights to Risks: Mental Health Implications for Pregnant Patients Following the Reversal of Roe v. Wade
Andrew S Murdock1, Angelica Arshoun1, Eduardo D Espiridion1
1Psychiatry, Drexel University College of Medicine, Philadelphia, USA.
The overturn of Roe v. Wade is linked to higher rates of acute stress and depressive episodes following non-spontaneous abortions. These mental health impacts were more pronounced in African American patients, highlighting disparities in care.
Area of Science:
- Reproductive Health
- Mental Health
- Public Health Policy
Background:
- The overturn of Roe v. Wade has impacted reproductive rights and access to abortion care in the US.
- This legal shift may influence the psychological well-being of individuals seeking abortion services.
- Previous research indicates a correlation between abortion access and mental health outcomes.
Purpose of the Study:
- To evaluate the incidence and prevalence of acute stress episodes (ASE) and depressive episodes in patients undergoing non-spontaneous abortions.
- To compare these mental health outcomes across distinct time periods: pre-COVID, COVID, and post-Roe v. Wade (pRvW).
- To examine disparities in mental health outcomes among different racial groups.
Main Methods:
- Utilized the TriNetX electronic health record database across 66 US healthcare organizations.
- Assessed diagnoses for depressive episodes (ICD-10-CM=F32) and acute stress episodes (ICD-10-CM=F43.0, F43.9, F43.11).
- Employed relative risk and Chi-squared tests to compare outcomes across pre-COVID (2017-2019), COVID (2020-2022), and pRvW (2022-2024) periods, analyzing racial group differences from 2017-2024.
Main Results:
- The prevalence of both depressive and acute stress episodes showed an increasing trend over time.
- The incidence of depressive episodes was lowest during COVID and highest in the pRvW period.
- The incidence of acute stress episodes increased during the COVID and pRvW periods, with no significant statistical difference between these two.
- Depressive episode prevalence significantly increased among African American patients (p=0.0146).
Conclusions:
- The overturn of Roe v. Wade appears associated with increased incidence and prevalence of acute psychiatric diagnoses post-non-spontaneous abortion.
- Certain racial groups, particularly African Americans, experienced disproportionately higher rates of depressive episodes.
- Findings underscore the necessity for enhanced psychological support services, especially within marginalized communities affected by reproductive rights changes.
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