Prevalence, clinical characteristics, and outcomes of carotid web in Chinese patients with acute ischemic stroke due to intracranial large vessel occlusion
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View abstract on PubMed
Summary
This summary is machine-generated.Carotid web (CaW) affects 3.99% of Chinese stroke patients, particularly younger individuals. While thrombectomy offers favorable outcomes for CaW-related strokes, recurrence necessitates further prevention research.
Area Of Science
- Neurology
- Vascular Surgery
- Stroke Medicine
Background
- Carotid web (CaW) is an emerging cause of embolic stroke, especially in young adults.
- Limited data exists on CaW prevalence and outcomes in Asian populations.
- This study focuses on CaW in Chinese patients with anterior circulation large vessel occlusion (LVO).
Purpose Of The Study
- To determine the prevalence of CaW in Chinese patients with anterior circulation LVO.
- To analyze the clinical characteristics and outcomes of CaW-associated LVO.
- To evaluate the effectiveness of mechanical thrombectomy for CaW-related strokes.
Main Methods
- Retrospective analysis of 401 patients undergoing mechanical thrombectomy for anterior circulation LVO.
- Data collected included demographics, clinical information, and stroke etiology.
- CaW diagnosis confirmed via digital subtraction angiography (DSA).
Main Results
- Symptomatic CaW identified in 3.99% (16/401) of patients, more common in younger individuals.
- Successful reperfusion (mTICI 2b-3) and favorable 90-day outcomes (mRS 0-2) were significantly higher in CaW patients (93.8%) versus non-CaW patients (45.7%).
- CaW was associated with significantly better post-thrombectomy outcomes (OR=9.70). Stroke recurrence occurred in 20% over 29 months.
Conclusions
- CaW prevalence in Chinese acute anterior circulation LVO stroke is 3.99%.
- CaW is linked to better outcomes after thrombectomy but carries a risk of recurrence.
- Further research is needed for optimal stroke prevention strategies in CaW patients.
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