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Updated: Jan 15, 2026

A Technical Guide for Performing Spectroscopic Measurements on Metal-Organic Frameworks
Published on: April 28, 2023
Oxygen Vacancy Engineering in Metal-Organic Frameworks Regulates the Generation of Reactive Oxygen Species (ROS) for
Jianwen Yang1,2, Lin Ye3, Dong-Pyo Kim2
1College of Carbon Neutrality Future Technology, Sichuan University, Chengdu 610065, Sichuan, P. R. China.
Abstract:
The synthesis of nitrogen-containing structural motifs with high efficiency under mild conditions is challenging. Herein, controllable regulation of reactive oxygen species (ROS) in NH2-MIL-125(Ti) via oxygen vacancies engineering is achieved to effectively promote the photocatalytic C═N and C-N coupling to synthesize imines and benzimidazole compounds under mild conditions. The oxygen vacancies and structural integrity in NH2-MIL-125(Ti) can be well-controlled by facilely changing the temperature during mild heat treatment. Compared with pristine NH2-MIL-125(Ti), the NH2-MIL-125(Ti)-derived NM-Vo-T show stronger capacities to photoreduce oxygen to form ROS including superoxide anion radicals (O2•-) and hydroxyl radicals (•OH), leading to obviously improved photocatalytic activity for both amine oxidation to imines and C-N coupling between diamines and ethanol to form benzimidazole. This work not only offers an effective way toward efficient C═N and C-N coupling but, more importantly, provides significant guidance for the design of novel photocatalysts for the synthesis of fine chemicals in a green way.
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