Related Experiment Video
Updated: Jan 15, 2026
Characterization and Functional Prediction of Bacteria in Ovarian Tissues
Published on: October 23, 2021
Research Communication: An Observational Cohort Study on Risk of Ovarian Cancer in Women with Irritable Bowel
Andrea Shin1, Huiping Xu2, Rachel Sarnoff1
1Vatche and Tamar Manoukian Division of Digestive Diseases, University of California, Los Angeles, California, USA.
Abstract:
We compared ovarian cancer incidence between women with and without an index irritable bowel syndrome (IBS) diagnosis using administrative claims data. Risk of ovarian cancer was higher at 3 (hazard ratio [HR] = 1.71, 95% CI: 1.08-2.70, p = 0.02) and 6 (HR = 1.43, 95% CI: 1.06-1.93, p = 0.02) months after an index IBS diagnosis, but not at time points after 8 months, in women with IBS compared to those without. Some women with symptoms of ovarian cancer may be misdiagnosed with IBS, although IBS is not causally linked to ovarian cancer. Further studies are needed to validate findings and clarify when ovarian cancer screening may be warranted.
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