Nanoparticles-based lateral flow immunochromatographic strip for detection of foodborne pathogen: A review

The harmful effects of foodborne pathogens (such as Salmonella and Listeria monocytogenes) on human health are one of the widely concerned food safety issues worldwide. Traditional methods for detecting foodborne pathogens are often cumbersome, time-consuming, and costly. It is necessary to develop fast, simple, and sensitive detection technologies. Recently, the lateral flow immunochromatography (LFIA) has attracted attention. Here, we summarize the latest developments in the detection of common foodborne pathogens using recognition elements such as antibodies, single chain antibodies, peptides, nanobodies, and phages in 2020-2024. We discussed how to apply colorimetric nanoparticles, luminescent nanomaterials, photothermal nanomaterials, and magnetic nanomaterials to LFIA for detecting foodborne pathogens. Representative examples have been selected to illustrate the potential mechanisms of each strategy in augmenting signal strength, along with their prospective applications in LFIA. Finally, the advantages, limitations, challenges, and opportunities of using LFIA for the diagnosis of foodborne pathogens were discussed.