Secure and interpretable lung cancer prediction model using mapreduce private blockchain federated learning and XAI
Khan Muhammad Adnan1, Taher M Ghazal2, Muhammad Saleem3
1Pattern Recognition and Machine Learning Lab, Faculty of Artificial Intelligence and Software, Gachon University, Seongnam-si, 13557, Republic of Korea.
Scientific Reports
|October 13, 2025
Summary
This study introduces a novel AI model for lung cancer prediction, integrating MapReduce, Private Blockchain, Federated Learning, and Explainable AI. The model achieves 98.21% accuracy, enhancing early detection and addressing data privacy and interpretability challenges in healthcare.
Area of Science:
- Artificial Intelligence in Oncology
- Medical Informatics
- Computational Biology
Background:
- Lung cancer remains a leading cause of cancer mortality globally.
- Effective early detection is crucial for reducing lung cancer mortality rates.
- Existing predictive models face challenges including high computational costs, data privacy concerns, limited data sharing, and lack of interpretability.
Purpose of the Study:
- To develop a novel, integrated AI framework for accurate and secure lung cancer prediction.
- To overcome the limitations of conventional predictive models in handling large datasets and ensuring data privacy.
- To enhance the interpretability of AI models for clinical application.
Main Methods:
- Utilized MapReduce for efficient processing of large-scale lung cancer datasets.
- Implemented Private Blockchain for secure, immutable, and tamper-proof patient data management.
- Employed Federated Learning (FL) to enable collaborative model training across institutions without compromising patient privacy.
- Integrated Explainable Artificial Intelligence (XAI) to enhance model transparency and trustworthiness for clinicians.
Main Results:
- The proposed integrated framework achieved a high accuracy of 98.21% in lung cancer prediction.
- Demonstrated a significantly low miss rate of 1.79%.
- Outperformed previous approaches in terms of accuracy, privacy preservation, scalability, and interpretability.
Conclusions:
- The novel AI model offers a secure, interpretable, and scalable solution for lung cancer prediction.
- The integration of MapReduce, Private Blockchain, FL, and XAI sets a new benchmark for AI in healthcare.
- The model's high performance and enhanced features support improved clinical decision-making and patient outcomes.
