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Updated: Jan 15, 2026

Closure of a Patent Foramen Ovale PFO: An Intervention Sequence
Published on: December 23, 2022
Asian-Pacific Expert Opinion on Patent Foramen Ovale Closure: Review of New Evidence and Focused Update
Jong S Kim1, Hans Cristoph Diener2, Ting-Ting Low3
1Department of Neurology, Gangneung Asan Hospital, Gangneung, Korea.
Abstract:
In 2020, clinical experts from leading Asian-Pacific cardiology and neurology centers published an expert opinion and consensus statement on transcatheter patent foramen ovale (PFO) closure for patients in the Asian-Pacific region. Given recent evidence and new insights, an update of this expert opinion is necessary on certain topics. This focused update reviews evidence on PFO closure in elderly and migraine patients, along with the use of contrast transcranial Doppler ultrasound as a screening tool. This update reflects the consensus reached by Asian-Pacific clinical experts during the Asia-Pacific Heart-Brain Summit (October 3, 2024, Bangkok, Thailand).

