Optimization of Aspiration Pressure in Oocyte Retrieval Using Reduced Needles.

Area of Science:

• Reproductive Medicine
• In Vitro Fertilization (IVF)
• Oocyte Retrieval Techniques

Background:

• Reduced-diameter needles are increasingly used in oocyte retrieval due to decreased pain.
• Optimal aspiration pressure for these reduced needles has not been established.
• Higher aspiration pressure is generally needed for smaller diameter needles.

Purpose of the Study:

• To investigate the optimal aspiration pressure for reduced-tip needles in oocyte retrieval.
• To compare clinical outcomes between two aspiration pressures (230 mmHg vs. 160 mmHg) using reduced needles.

Main Methods:

• Retrospective analysis of 223 oocyte retrieval cycles.
• Utilized reduced needles (20-gauge tip, 17-gauge shaft).
• Compared outcomes at aspiration pressures of 230 mmHg and 160 mmHg.

Main Results:

• No significant differences in oocyte yield or fertilization rates between pressures when considering all patients.
• Shorter procedure time observed at 160 mmHg for patients with anti-Müllerian hormone (AMH) ≥1.2.
• Significantly higher fertilization rates at 160 mmHg across all AMH levels (AMH ≥1.2 and AMH <1.2).

Conclusions:

• High aspiration pressure (230 mmHg) was associated with decreased fertilization rates in reduced needles.
• Aspiration pressure adjustment should consider the thick shaft diameter, not just the thin tip.
• 160 mmHg may be a more suitable aspiration pressure for reduced needles in oocyte retrieval.