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Enhancing food safety and quality: multiplex detection using smart nanostructured molecular logic technologies
Xinru Yu1,2,3, Hongbin Pu1,2,3, Da-Wen Sun1,2,3,4
1School of Food Science and Engineering, South China University of Technology, Guangzhou, China.
Critical Reviews in Food Science and Nutrition
|October 14, 2025
Summary
Smart nanostructured molecular logic technologies (SNMLT) offer advanced multi-target detection for food safety. This review highlights SNMLT
Area of Science:
- Food analysis and safety
- Nanotechnology in sensing
- Molecular logic systems
Background:
- Multi-target detection is crucial for comprehensive food safety and quality assessment.
- Smart nanostructured molecular logic technologies (SNMLT) are emerging for multiplex food analysis.
- Component materials-based SNMLT show promise due to rapid response, multifunctionality, and high sensitivity.
Purpose of the Study:
- To provide a comprehensive review of SNMLT sensing platforms for food multi-target detection.
- To summarize the principles, classification, component materials, and signal output strategies of SNMLT.
- To highlight the applications of SNMLT in detecting physical, biological, and chemical hazards in food.
Main Methods:
- Review of existing literature on SNMLT for food analysis.
- Description of SNMLT operational principles and classification.
- Summary of component materials and signal output mechanisms.
- Analysis of SNMLT applications in various food safety contexts.
Main Results:
- SNMLT offers a wide detection range and strong anti-interference capabilities for multiplex assays.
- Component materials-based SNMLT are effective for simultaneous analysis of multiple food analytes.
- Applications span physical, biological, and chemical hazard detection, as well as food quality assessment.
Conclusions:
- SNMLT presents a powerful platform for advanced food safety monitoring.
- Future research should focus on integrating SNMLT with artificial intelligence for user-friendly sensing devices.
- Further development is needed to address challenges and enhance the practical application of SNMLT in food analysis.
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