Related Experiment Video

Updated: Jan 6, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

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Finnish Healthcare Professionals' Online Searches for Paediatric Oral Antibiotics: COVID-19 Impact, 2017-2023

M Mukka1, O Helve2,3, P Mustonen4

  • 1University of Helsinki, Helsinki, Finland.

Acta Paediatrica (Oslo, Norway : 1992)
|October 14, 2025
PubMed

Insights

Healthcare professionals

Area of Science:

  • Pediatric infectious diseases
  • Antimicrobial stewardship
  • Public health surveillance

Background:

  • Physician's Databases in Finland are a key online resource for healthcare professionals.
  • Understanding trends in antibiotic use and diagnoses is crucial for public health.
  • The COVID-19 pandemic significantly impacted healthcare practices and information-seeking behaviors.

Purpose of the Study:

  • To analyze trends in healthcare professionals' online searches for pediatric oral antibiotics.
  • To examine antibiotic prescriptions and COVID-19 diagnoses in children under 5-6 years.
  • To correlate information-seeking behavior with clinical antibiotic use.

Main Methods:

  • Analyzed 1,231,383 antibiotic searches from Physician's Databases (2017-2023).
  • Examined 492,407 pediatric antibiotic prescriptions and 42,293 pediatric COVID-19 diagnoses.
  • Focused on seven common oral antibiotic suspensions, particularly amoxicillin.

Main Results:

  • Amoxicillin was the most searched antibiotic, exhibiting seasonal patterns.
  • A significant decrease in antibiotic searches and prescriptions occurred from March 2020 to August 2021.
  • Searches for amoxicillin increased with two major peaks between September 2021 and August 2023.

Conclusions:

  • Online information-seeking for pediatric antibiotics decreased sharply post-COVID-19 onset but recovered within two years.
  • Healthcare professionals' search trends reflect shifts in antibiotic use.
  • Monitoring online search behavior can offer insights into clinical antibiotic utilization in children.
Abstract

Keywords:
COVID‐19anti‐bacterial agentsbacterial infectionshealth personnel

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