Nonsurgical lower eyelid rejuvenation using a novel 1064-nm Nd:YAG laser with a 650- microsecond pulse duration

The lower eyelid region is prone to age-related concerns, including wrinkles and dark circles, resulting from structural changes, such as collagen depletion, fat prolapse, and reduced elasticity. Traditional treatments, such as surgery, fillers, and conventional lasers have limitations including risks, downtime, and variable efficacy. This study evaluated the safety and efficacy of a novel 1064-nm neodymium-doped yttrium aluminum garnet (Nd: YAG) laser with a 650 µs pulse duration for noninvasive lower eyelid rejuvenation targeting wrinkles and dark circles. Sixteen participants underwent five weekly treatment sessions, with evaluations at baseline, during treatment, and 1 month post-treatment. The outcomes included quantitative assessments of wrinkles and pigmentation using a facial skin analyzer and participant satisfaction scores. As a result, no significant side effects occurred apart from transient erythema, and participant satisfaction was high. Statistically significant improvements were observed in wrinkle level (baseline: 4.15 ± 1.09; post-treatment: 3.32 ± 1.13, p < 0.001) and dark circle scores (baseline: 69.63 ± 14.09; post-treatment: 77.00 ± 13.59, p < 0.001). The novel 1064 nm Nd: YAG laser with a 650 µs pulse duration offered a painless, downtime-free alternative to traditional treatments and demonstrated significant efficacy in lower eyelid rejuvenation.