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Updated: Jun 25, 2026

Use of a Rat Model to Study Ventral Abdominal Hernia Repair
05:47

Use of a Rat Model to Study Ventral Abdominal Hernia Repair

Published on: October 2, 2017

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Mesh removal and ventral hernia repair with long-term absorbable mesh in case of mesh infection

Gaëtan-Romain Joliat1,2, Guillaume Passot3, Benoit Romain4

  • 1Department of Visceral Surgery, Lausanne University Hospital CHUV, University of Lausanne (UNIL), Lausanne, Switzerland. gaetan.joliat@gmail.com.

Hernia : the Journal of Hernias and Abdominal Wall Surgery
|October 14, 2025
PubMed
Abstract

Insights

Explanting infected ventral hernia mesh and replacing it with an absorbable mesh shows promising long-term results for hernia recurrence. This strategy has high short-term complication rates but low rates of repeat mesh removal.

Area of Science:

  • Abdominal Surgery
  • Biomaterials Science

Background:

  • Mesh infection is a rare but serious complication following ventral hernia repair.
  • Infected mesh often requires removal, potentially leading to hernia recurrence.

Purpose of the Study:

  • To evaluate the outcomes of explanting infected mesh and inserting a long-term absorbable mesh.
  • To compare results in acute mesh infection (AMI) and chronic mesh infection (CMI) cases.

Main Methods:

  • Retrospective study of 29 patients across two tertiary centers (2017-2024).
  • Patients underwent infected mesh explantation and poly-4-hydroxybutyrate mesh implantation.
  • Hernia recurrence was the primary endpoint; AMI defined as infection within 90 days.

Main Results:

  • 14 AMI and 15 CMI patients included; most meshes were intraperitoneal.
  • High rates of new mesh implantation in the retromuscular space and some component separations were noted.
  • Median hospital stays were 7-10 days; 60-64% experienced postoperative complications. Hernia recurrence was 21% in AMI and 0% in CMI groups.

Conclusions:

  • The strategy of mesh explantation and absorbable mesh insertion shows good long-term outcomes with low recurrence and re-explantation rates.
  • High short-term morbidity was observed.
  • Further research with longer follow-up is needed to fully assess recurrence and reinfection risks.
Keywords:
Abdominal wall surgeryComplicationsInfectionMorbidity

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