Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chirality in Nature02:30

Chirality in Nature

16.4K
Chirality is the most intriguing yet essential facet of nature, governing life’s biochemical processes and precision. It can be observed from a snail shell pattern in a macroscopic world to an amino acid, the minutest building block of life. Most of the snails around the world have right-coiled shells because of the intrinsic chirality in their genes. All the amino acids present in the human body exist in an enantiomerically pure state, except for glycine - the sole achiral amino acid.
16.4K
Chirality02:25

Chirality

28.9K
Chirality is a term that describes the lack of mirror symmetry in an object. In other words, chiral objects cannot be superposed on their mirror images. For example, our feet are chiral, as the mirror image of the left foot, the right foot, cannot be superposed on the left foot.
Chiral objects exhibit a sense of handedness when they interact with another chiral object. For example, our left foot can only fit in the left shoe and not in the right shoe. Achiral objects — objects that have...
28.9K
Prochirality02:05

Prochirality

4.8K
The concept of prochirality leads to the nomenclature of the individual faces of a molecule and plays a crucial role in the enantioselective reaction. It is a concept where two or more achiral molecules react to produce chiral products. A typical process is the reaction of an achiral ketone to generate a chiral alcohol. Here, the achiral reactant reacts with an achiral reducing agent, sodium borohydride, to generate an equimolar mixture of the chiral enantiomers of the product. For example, an...
4.8K
Chirality at Nitrogen, Phosphorus, and Sulfur02:30

Chirality at Nitrogen, Phosphorus, and Sulfur

6.8K
Chirality is most prevalent in carbon-based tetrahedral compounds, but this important facet of molecular symmetry extends to sp3-hybridized nitrogen, phosphorus and sulfur centers, including trivalent molecules with lone pairs. Here, the lone pair behaves as a functional group in addition to the other three substituents to form an analogous tetrahedral center that can be chiral.
A consequence of chirality is the need for enantiomeric resolution. While this is theoretically possible for all...
6.8K
SN1 Reaction: Stereochemistry02:15

SN1 Reaction: Stereochemistry

10.1K
This lesson provides an in-depth discussion of the stereochemical outcomes in an SN1 reaction.
In the first step of an SN1 reaction, the bond between the electrophilic carbon and the leaving group ionizes to generate the carbocation intermediate. The second step of the mechanism is the nucleophilic attack.
In the formed carbocation, the positively charged carbon is sp2 hybridized with a trigonal planar geometry. As all the three substituents lie on the same plane, a plane of symmetry for the...
10.1K
Molecules with Multiple Chiral Centers02:25

Molecules with Multiple Chiral Centers

14.7K
Molecules that possess multiple chiral centers can afford a large number of stereoisomers. For instance, while some molecules like 2-butanol have one chiral center, defined as a tetrahedral carbon atom with four different substituents attached, several molecules like butane-2,3-diol have multiple chiral centers. A simple formula to predict the number of stereoisomers possible for a molecule with n chiral centers is 2n. However, there can be a lower number where some of the stereoisomers are...
14.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optimal experiment design for practical parameter identifiability and model discrimination.

Mathematical biosciences·2026
Same author

Problems, Progress and Perspectives in Mathematical and Computational Biology.

Bulletin of mathematical biology·2026
Same author

Networked collective dynamics in animal ecology and cell biology.

Physics of life reviews·2026
Same author

Growth rate-driven modelling suggests that phenotypic adaptation drives drug resistance in BRAFV600E-mutant melanoma.

Communications biology·2026
Same author

First Explore, Then Settle: A Theoretical Analysis of Evolvability as a Driver of Adaptation.

Bulletin of mathematical biology·2026
Same author

Persistent Homology Classifies Parameter Dependence of Patterns in Turing Systems.

Bulletin of mathematical biology·2025

Related Experiment Video

Updated: Jan 6, 2026

A Micropatterning Assay for Measuring Cell Chirality
08:07

A Micropatterning Assay for Measuring Cell Chirality

Published on: March 11, 2022

2.6K

Chase-and-Run and Chirality in Nonlocal Models of Pattern Formation.

Thomas Jun Jewell1, Andrew L Krause2, Philip K Maini3

  • 1Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Andrew Wiles Building, Radcliffe Observatory Quarter, Woodstock Road, Oxford, OX2 6GG, United Kingdom. jewell@maths.ox.ac.uk.

Bulletin of Mathematical Biology
|October 14, 2025
PubMed
Summary

Chirality, or left-right asymmetry, in chase-and-run dynamics can generate complex patterns and structures. This study explores how angled movement influences population dynamics and pattern formation in biological systems.

Keywords:
behavioural lateralisationchase-and-runchiralityintegro-differential equationleft-right asymmetrynonlocalpattern formation

More Related Videos

Coulomb Explosion Imaging as a Tool to Distinguish Between Stereoisomers
08:51

Coulomb Explosion Imaging as a Tool to Distinguish Between Stereoisomers

Published on: August 18, 2017

10.8K
Studying Cell Rolling Trajectories on Asymmetric Receptor Patterns
04:24

Studying Cell Rolling Trajectories on Asymmetric Receptor Patterns

Published on: February 13, 2011

9.8K

Related Experiment Videos

Last Updated: Jan 6, 2026

A Micropatterning Assay for Measuring Cell Chirality
08:07

A Micropatterning Assay for Measuring Cell Chirality

Published on: March 11, 2022

2.6K
Coulomb Explosion Imaging as a Tool to Distinguish Between Stereoisomers
08:51

Coulomb Explosion Imaging as a Tool to Distinguish Between Stereoisomers

Published on: August 18, 2017

10.8K
Studying Cell Rolling Trajectories on Asymmetric Receptor Patterns
04:24

Studying Cell Rolling Trajectories on Asymmetric Receptor Patterns

Published on: February 13, 2011

9.8K

Area of Science:

  • Mathematical Biology
  • Nonlinear Dynamics
  • Pattern Formation

Background:

  • Chase-and-run dynamics are prevalent in nature, involving pursuit-evasion interactions.
  • Angled movement, characterized by lateralization or chirality, is observed in systems like zebrafish patterns and animal motion.
  • Existing models often simplify movement to straight lines, overlooking the impact of angled trajectories.

Purpose of the Study:

  • To investigate the role of chirality in shaping emergent patterns within nonlocal advection-diffusion models.
  • To extend these models to accommodate arbitrary angled movement.
  • To uncover novel behaviors and dynamical structures arising from chiral chase-and-run dynamics.

Main Methods:

  • Development of nonlocal (integro-differential) advection-diffusion models incorporating angled movement.
  • Extension of models to allow movement at arbitrary angles.
  • Linear stability analysis to identify underlying physical mechanisms.

Main Results:

  • Chirality enhances pattern formation and suppresses oscillations in chase-and-run systems.
  • Novel dynamical structures, such as rotating pulses, emerge due to chirality.
  • Chirality influences population mixing and separation dynamics.
  • Linear stability analysis reveals mechanisms but also limitations in capturing complex dynamics.

Conclusions:

  • Chirality plays a significant role in pattern formation beyond simple symmetry breaking.
  • Angled movement in chase-and-run dynamics leads to rich and complex behaviors.
  • The study highlights the importance of incorporating chirality in ecological and cellular patterning models.