Pulmonary Amyloidosis

Amyloidosis is a heterogeneous group of rare diseases characterized by the deposition of misfolded and insoluble proteins in tissues. Lung involvement, airways or parenchyma, is relatively common, but usually mild. Some patients may develop chronic progressive forms or experience life-threatening complications. In this review, we summarize the most recent advances in the comprehension of molecular mechanisms and classification of amyloidosis. We then illustrate the different forms of lung amyloidosis and the current treatment options. Increased awareness in the medical community and the creation of referral centers' networks are of paramount importance to ensure adequate management and access to treatment.