Endometriosis Support and Development of Digital Technology-Based Interventions: Systematic Review
Tivizio Pavic1, Kévin Nadarajah1,2, Alain Somat1
1Laboratoire de Psychologie: Cognition, Comportement, Communication (LP3C), Univ Rennes, Rennes, France.
JMIR Human Factors
|October 14, 2025
Summary
Digital health interventions show promise for managing endometriosis, offering physical and psychological benefits. However, their development and evaluation methodologies are inconsistent, necessitating structured frameworks for optimal patient support.
Area of Science:
- Digital health interventions
- Endometriosis management
- Systematic review
Background:
- Endometriosis affects 1 in 10 women globally, impacting physical, psychological, and social well-being.
- Digital technologies are increasingly used in endometriosis management, but their development and efficacy lack systematic review.
- Existing interventions aim to improve daily life for endometriosis patients.
Purpose of the Study:
- To systematically review the development, design, and effectiveness of digital health interventions for endometriosis.
- To characterize the methodologies employed in digital health interventions for endometriosis management.
Main Methods:
- Systematic literature search across 7 databases (2010-2024).
- Analysis using the Design and Evaluation of Digital Health Interventions (DEDHI) framework (4 phases).
- Inclusion of 10 articles from 381 retrieved studies.
Main Results:
- Six distinct digital health interventions were identified, yielding physical and psychological benefits.
- Significant disparities observed in DEDHI phase completion (Phase 1: 90%, Phase 2: 30%, Phase 3: 40%, Phase 4: 20%).
- Intervention objectives included pain management (83%), disease information (67%), and psychosocial support (33%).
Conclusions:
- An emerging, yet limited and heterogeneous, body of literature exists on digital technology for endometriosis.
- Variability in methodologies hinders generalizability, requiring nuanced interpretation.
- Digital interventions offer value for endometriosis support, emphasizing the need for structured development frameworks.


