What Is the Association Between Music-Related Leisure Activities and Dementia Risk? A Cohort Study

To determine whether engagement in music-related leisure activities is associated with a reduced risk of dementia and cognitive impairment no dementia (CIND), as well as better cognitive wellbeing in initially cognitively healthy older adults. Here, cognitive wellbeing includes maintaining good cognitive function as well as quality of life. Potential effect modification by education was also investigated.

This study used secondary data from the ASPirin in Reducing Events in the Elderly (ASPREE) study, and the ASPREE Longitudinal Study of Older Persons (ALSOP) sub-study. Included were 10,893 community-dwelling Australian adults who were 70 years and older, without dementia diagnosis at recruitment to the study. Cox proportional hazard regression models were used to determine the association between level of music engagement (listening to music, playing an instrument, and a combination of both) and dementia risk from year 3 onwards. Linear mixed models were used to investigate the association with cognitive wellbeing. Analyses adjusted for age, gender and level of education completed.

Always listening to music, compared with never/rarely/sometimes, was associated with a 39% decreased risk of dementia (95% CI = 0.45,0.82, p = 0.001), and a 17% decreased risk of CIND (95% CI = 0.74, 0.92, p = 0.001). Playing an instrument (often/always) was associated with a 35% decreased dementia risk only (95% CI = 0.42,0.99, p = 0.047). Participants who both listened to and played music had a 33% decreased dementia risk (95% CI = 0.51,0.89, p = 0.006) and a 22% decreased CIND risk (95% CI = 0.65,0.92, p = 0.004). Always listening to music was associated with better global cognition and memory over time (p < 0.001, p = 0.004, respectively), but not the other cognitive domains. Engagement in music-related activities was not associated with changes in subjective cognitive wellbeing. In general, findings were stronger in individuals with over 16 years of education.

These results highlight music as a potential promising, accessible strategy to help reduce cognitive impairment and delay the onset of dementia in later life.