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Updated: Jan 15, 2026
Preparation, Procedures and Evaluation of Platelet-Rich Plasma Injection in the Treatment of Knee Osteoarthritis
Published on: January 4, 2019
Unexpected Intramedullary Canal Fill During Ultrasound-Guided Subchondral Intraosseous Platelet-Rich Plasma
Tsung Ju Wu1,2, Wei-Cheng Liao3, Chih-Wei Lee4
1Regenerative Medicine, Reboot Clinics, Changhua, TWN.
Ultrasound-guided intraosseous injections for knee osteoarthritis can be complicated by intramedullary misplacement. Recognizing specific ultrasound Doppler patterns is crucial for accurate needle placement and effective treatment.
Area of Science:
- Orthopedics
- Radiology
- Regenerative Medicine
Background:
- Ultrasound-guided subchondral intraosseous (IO) injection is a common treatment for knee osteoarthritis (OA) with bone marrow lesions (BMLs).
- Accidental intramedullary misplacement, or "canal fill," is a rare but potential complication of this procedure.
- Osteoporosis can increase the risk of needle misplacement during IO injections.
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