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Refractory Digital Ulcers in Systemic Sclerosis Sine Scleroderma Associated With Antiphospholipid Syndrome: A
Inês Almeida1, Liliana Saraiva1, Vera Romão2
1Rheumatology, Unidade Local de Saúde Viseu Dão-Lafões, Viseu, PRT.
Systemic sclerosis sine scleroderma (ssSSc) with secondary antiphospholipid syndrome (APS) is rare. This case highlights APS diagnosis in a patient with refractory digital ulcers (DUs) and pulmonary embolism, leading to DU healing with anticoagulation.
Area of Science:
- Rheumatology
- Vascular Medicine
- Immunology
Background:
- Digital ulcers (DUs) are a severe manifestation of vasculopathy in systemic sclerosis (SSc).
- Antiphospholipid syndrome (APS) is a rare but treatable cause of vasculopathy, particularly in patients with SSc sine scleroderma (ssSSc).
- Diagnosing secondary APS in ssSSc patients with refractory DUs is challenging but crucial.
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