Related Experiment Video

Updated: Jan 15, 2026

High-definition Transcranial Direct Current Stimulation over Right Dorsolateral Prefrontal Cortex to Enhance Metacognitive Sensitivity
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High-definition Transcranial Direct Current Stimulation over Right Dorsolateral Prefrontal Cortex to Enhance Metacognitive Sensitivity

Published on: September 26, 2025

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High-Definition Transcranial Direct Current Stimulation Improves Pain Empathy: A Randomized, Double-Blind, and

Zhengyu Hu1,2, Yurong Wen3,4, Beibei Feng1,5,6

  • 1Department of Rehabilitation Medicine, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, People's Republic of China.

Journal of Pain Research
|October 15, 2025
PubMed
Summary

High-definition transcranial direct current stimulation (HD-tDCS) at 2mA intensity enhanced affective pain empathy by increasing unpleasantness perception. However, it did not improve cognitive empathy or pain ratings, suggesting intensity-dependent effects.

Keywords:
dorsolateral prefrontal cortexevent-related potentialpain empathytranscranial direct current stimulation

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