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Establishment of a Multidisciplinary Pediatric Lupus Care Clinic at a Tertiary Center

Esra Meidan1, Ankana Daga2, Amy Mcdonough1

  • 1Division of Immunology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.

Journal of Multidisciplinary Healthcare
|October 15, 2025
PubMed

Insights

A specialized pediatric lupus clinic improved care for childhood-onset systemic lupus erythematosus (cSLE) patients. This multidisciplinary approach led to better outcomes and reduced hospitalizations for these complex autoimmune disease cases.

Area of Science:

  • Pediatric Rheumatology
  • Autoimmune Diseases
  • Nephrology

Background:

  • Childhood-onset systemic lupus erythematosus (cSLE) presents with greater severity and organ involvement than adult-onset SLE.
  • Lupus nephritis is a significant concern in pediatric patients, necessitating specialized care.
  • Existing care models may not adequately address the complex needs of cSLE patients.

Purpose of the Study:

  • To evaluate the effectiveness of a multidisciplinary pediatric lupus clinic in managing cSLE.
  • To assess the impact of integrated care on patient outcomes and healthcare utilization.
  • To explore a model for comprehensive and coordinated care in pediatric autoimmune diseases.

Main Methods:

  • Establishment of a multidisciplinary clinic integrating rheumatology, nephrology, nursing, and social work.
  • Implementation of a team-based model for shared decision-making and personalized treatment.
  • Tracking of clinical outcomes (SLEDAI-2K scores) and healthcare utilization (ER visits, admissions).

Main Results:

  • Improved average SLEDAI-2K scores in the pediatric lupus clinic population.
  • Achieved 100% clinic follow-up rates.
  • Low rates of emergency room visits (15%) and inpatient admissions (4%) among high-risk patients.

Conclusions:

  • A multidisciplinary, team-based approach significantly enhances care delivery for cSLE patients.
  • This model demonstrates success in improving clinical outcomes and reducing healthcare utilization.
  • The clinic serves as a promising framework for equitable, high-quality pediatric lupus care.

Keywords:
childhood onset SLEchildhood-onset systemic lupus erythematosuslupus nephritismultidisciplinary carepediatric lupus

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