Related Experiment Video

Updated: Jan 15, 2026

Isolation of Human Atrial Myocytes for Simultaneous Measurements of Ca2+ Transients and Membrane Currents
10:53

Isolation of Human Atrial Myocytes for Simultaneous Measurements of Ca2+ Transients and Membrane Currents

Published on: July 3, 2013

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Impaired Atrial Mitochondrial Calcium Handling in Patients With Atrial Fibrillation

Julius Ryan D Pronto1,2, Fleur E Mason1,2, Eva A Rog-Zielinska3

  • 1Institute of Pharmacology and Toxicology (J.R.D.P., F.E.M., F.E.F., D.B., P.B., P.J.S., K.R., S.K., N.V.), University Medical Center Göttingen, Germany.

Circulation Research
|October 15, 2025
PubMed
Summary

Mitochondrial calcium handling is impaired in atrial fibrillation (AF), linked to cellular disorganization. Enhancing mitochondrial calcium uptake may prevent arrhythmias in AF patients.

Keywords:
atrial fibrillationcalcium signalingezetimibemicrotubulesmitochondria

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