Success Rates of Assisted Reproduction in Couples with Poor Ovarian Response and Oligospermia

Area of Science:

• Reproductive Medicine
• In Vitro Fertilization
• Andrology
• Gynecology

Background:

• Assisted reproductive medicine offers solutions for subfertility.
• Diminished ovarian response and oligozoospermia (low sperm count) are key challenges in IVF.
• Lifestyle factors impact fertility outcomes.

Purpose of the Study:

• To investigate the combined impact of poor ovarian response and oligozoospermia on intracytoplasmic sperm injection (ICSI) outcomes.
• To propose an optimal management strategy for couples with both conditions.
• To highlight the importance of both partners' health in achieving successful conception.

Main Methods:

• Analysis of ICSI outcomes in couples with diminished ovarian response and oligozoospermia.
• Comparison of fertilization, cleavage, and blastocyst rates.
• Evaluation of cycle cancellation rates.

Main Results:

• Oligozoospermia significantly reduced ICSI fertilization and cleavage rates.
• Poor ovarian responders had higher rates of cycle cancellation due to fewer embryos.
• Overall success rates were lower in couples with both male factor infertility and poor ovarian response.

Conclusions:

• Combined diminished ovarian response and oligozoospermia negatively impact IVF success.
• Personalized treatment approaches are essential for optimizing outcomes in these couples.
• Addressing both partners' fertility factors is critical for successful conception.