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Impaired Functional Brain-Heart Interplay Sustains Depressive Symptomatology.

Vincenzo Catrambone, Francesca Mura, Elisabetta Patron

    IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society
    |October 15, 2025
    PubMed
    Summary

    Depression involves impaired brain-heart communication. This study reveals hyperactivity in central-to-peripheral pathways and reduced vagal-to-central input in individuals with depressive symptoms.

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