Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Super-resolution Fluorescence Microscopy01:37

Super-resolution Fluorescence Microscopy

12.2K
Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been...
12.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Imaging of Neurovascular Compression in Thoracic Outlet Syndrome.

Annals of neurology·2026
Same author

Differentiation defects reposition sebaceous glands as inflammatory instigators in the early pathogenesis of hidradenitis suppurativa.

Frontiers in immunology·2026
Same author

A Multi-Omics Study of Comorbid Mechanisms Between Depression and Inflammatory Dermatoses Identifies FADS1 and TMEM258 as Therapeutic Targets.

Clinical, cosmetic and investigational dermatology·2026
Same author

Ultra-Wide-Field Noninvasive Imaging Through Scattering Media Via Physics-Guided Deep Learning.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Correction: Comprehensive insight on immune landscape in intracerebral hemorrhage patients with single‑cell RNA sequencing: from blood to hematoma.

Journal of neuroinflammation·2026
Same author

Peroxiredoxins in Stroke: Friends and Foes.

Cells·2026
Same journal

Gaussian-modulated continuous-variable quantum key distribution over 60 km fiber using an integrated silicon photonic receiver.

Optics letters·2026
Same journal

E2E-OCT: end-to-end joint learning model using optical coherence tomography images for vocal cord leukoplakia diagnosis.

Optics letters·2026
Same journal

Holographic generation of panoramic 3D scenes by concave ellipsoidal mirror reflection.

Optics letters·2026
Same journal

Dual-pilot phase recovery with pair-wise maximum-ratio combining for coherent PONs.

Optics letters·2026
Same journal

Mapping the whispering gallery modes of a CaF<sub>2</sub> disk resonator with half-tapered fibers to estimate the fundamental mode volume.

Optics letters·2026
Same journal

Quantitative estimation of deep-subwavelength scale via dark-field scattering axial energy concentration decay profiles.

Optics letters·2026
See all related articles

Related Experiment Video

Updated: Jan 15, 2026

Single Molecule Fluorescence Microscopy on Planar Supported Bilayers
20:00

Single Molecule Fluorescence Microscopy on Planar Supported Bilayers

Published on: October 31, 2015

14.4K

Single-photon CASSI: towards ultralow-light spectral imaging.

Haoze Song, Yibo Feng, Xilong Dai

    Optics Letters
    |October 15, 2025
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces a novel single-photon coded aperture snapshot spectral imaging (CASSI) system using single-photon avalanche diodes (SPAD) for enhanced ultralow-light spectral imaging. The system achieves significant performance improvements in challenging imaging scenarios.

    More Related Videos

    Ratiometric Calcium Imaging of Individual Neurons in Behaving Caenorhabditis Elegans
    11:26

    Ratiometric Calcium Imaging of Individual Neurons in Behaving Caenorhabditis Elegans

    Published on: February 7, 2018

    12.1K
    Low-energy Cathodoluminescence for OxyNitride Phosphors
    07:03

    Low-energy Cathodoluminescence for OxyNitride Phosphors

    Published on: November 15, 2016

    11.1K

    Related Experiment Videos

    Last Updated: Jan 15, 2026

    Single Molecule Fluorescence Microscopy on Planar Supported Bilayers
    20:00

    Single Molecule Fluorescence Microscopy on Planar Supported Bilayers

    Published on: October 31, 2015

    14.4K
    Ratiometric Calcium Imaging of Individual Neurons in Behaving Caenorhabditis Elegans
    11:26

    Ratiometric Calcium Imaging of Individual Neurons in Behaving Caenorhabditis Elegans

    Published on: February 7, 2018

    12.1K
    Low-energy Cathodoluminescence for OxyNitride Phosphors
    07:03

    Low-energy Cathodoluminescence for OxyNitride Phosphors

    Published on: November 15, 2016

    11.1K

    Area of Science:

    • Optics and Photonics
    • Image Processing
    • Computational Imaging

    Background:

    • Spectral imaging is crucial for various applications but is limited in ultralow-light conditions.
    • Existing coded aperture snapshot spectral imaging (CASSI) systems face challenges with sparse spatial sampling and lack of specialized networks for low-light data.

    Purpose of the Study:

    • To develop a highly sensitive snapshot spectral imaging system for ultralow-light conditions.
    • To integrate single-photon avalanche diodes (SPAD) with the CASSI framework for improved spectral and spatial information capture.

    Main Methods:

    • Developed an efficient spectral-spatial model tailored for ultralow-light imaging.
    • Created a SPAD-CASSI simulation algorithm incorporating calibrated photon counts, noise, and spectral-spatial encoding.
    • Designed a deep learning network for spectral reconstruction from simulated SPAD-CASSI data.
    • Simulated data from 450-650 nm across 8 channels at 64x32 resolution with 100 µs exposure at 0.15 lux.

    Main Results:

    • The proposed SPAD-CASSI system demonstrates significantly improved performance in snapshot spectral imaging under ultralow-light conditions.
    • Experimental validation across macroscopic, microscopic, and high-speed scenarios confirmed the system's robustness.
    • The deep learning approach effectively reconstructed spectral information from sparse, noisy data.

    Conclusions:

    • The integrated SPAD-CASSI system offers a robust solution for spectral imaging in challenging ultralow-light environments.
    • This advancement opens new possibilities for applications requiring high sensitivity and spectral resolution in low-light settings.